Last verified: April 2026. Prices, product availability, and English support change — confirm directly with the clinic or through Kanbi before booking.

Booking Profhilo Tokyo clinics will actually inject in English is a shorter shortlist than elsewhere — the product isn't PMDA-approved in Japan and is only available at clinics that import privately. This guide covers how Tokyo clinics approach skin boosters in 2026, realistic prices in both ¥ and $, and the English-speaking clinics foreigners most often end up at.

What to Know Before Profhilo in Tokyo

Profhilo is an Italian-manufactured bio-remodelling injection from IBSA — a high-concentration hyaluronic acid product (32 mg/ml, combining high and low molecular weight HA) designed to improve skin quality, hydration, and mild laxity rather than add volume like a traditional filler. The standard protocol uses the BAP (Bio Aesthetic Points) technique — five specific injection points per side on the face — with 2 ml per session and two sessions four weeks apart, then maintenance every 6 months. Tokyo clinics that offer Profhilo do so on a private import basis, which adds to the cost compared with markets where it's locally registered.

Product and technique options in the skin booster category:

  • Profhilo — the original bio-remodelling hyaluronic acid skin booster Tokyo patients most often ask about by name
  • Rejuran (Korean polynucleotide salmon-DNA) — a frequent alternative with different mechanism (DNA fragments stimulate dermal repair rather than HA-based hydration); commonly available
  • Restylane Vital / Skinbooster — a stabilized HA micro-injection product for hydration and skin quality
  • Juvederm Volite — Allergan's HA skin booster with 12 mg/ml crosslinked hyaluronic acid
  • Profhilo Body (for arms, décolletage, knees) and Profhilo Haenkenium — scalp and hair-line variant
  • BAP vs droplet vs multi-needle techniques — most Tokyo clinics stick to the manufacturer's BAP protocol for facial Profhilo
  • Combination plans pairing Profhilo with Ultherapy, Thermage FLX, Picolaser, or fractional laser over months

Practical notes for foreigners:

  • Expect small, slightly visible bumps at each BAP injection point for 24–72 hours — plan accordingly if you have events
  • Mild redness and bruising are common; product settles into the skin quickly given the droplet-like behavior of Profhilo
  • Results build over 4–8 weeks — the first session alone rarely delivers what the brand photography shows
  • Patients with significant volume loss or deep folds are not ideal candidates — Profhilo is a quality treatment, not a volumizer
  • Consultation fees (¥3,300–¥5,500 / ~$22–$37) are usually separate from the treatment price
  • Confirm the vial is genuine Profhilo with an intact IBSA hologram and expiration date — private-import products should have clear lot traceability

5 English-Speaking Profhilo Clinics in Tokyo

Shirono Clinic — Ebisu

A long-running aesthetic dermatology group with an Ebisu flagship that sees many foreign patients. Shirono offers imported Profhilo alongside Rejuran and several filler skin boosters, and commonly plans Profhilo courses combined with Picolaser or Ultherapy on separate visits for a broader skin-quality plan.

  • English level: English-speaking staff available by appointment; written consent forms in English
  • Price range: ¥66,000–¥99,000 ($440–$660) per Profhilo session; ¥110,000–¥180,000 ($733–$1,200) for a two-session course
  • Best for: structured two-session Profhilo courses, skin-quality plans that stack multiple modalities over months
  • Caveat: English-language slots book out 2–3 weeks ahead, especially for weekend appointments

Tokyo Midtown Clinic — Roppongi

The dermatology department inside Tokyo Midtown Clinic runs a more medical-feeling injection practice. They offer private-import Profhilo to appropriate candidates and will honestly steer patients toward volume-based fillers, Rejuran, or device-based treatments when Profhilo isn't the right tool.

  • English level: full English intake; several physicians trained or board-certified abroad
  • Price range: ¥77,000–¥110,000 ($513–$733) per session
  • Best for: first-time skin booster patients, medical-grade consultation about whether Profhilo is actually the right fit
  • Caveat: priced at the upper end of the market and package discounts are minimal

Minami Aoyama Skin Care Clinic — Aoyama

Well-known among expats in central Tokyo, with Profhilo, Rejuran, Restylane Skinbooster, and Juvederm Volite all on the menu — useful for directly comparing skin booster injection Tokyo options in a single consult. They also integrate Profhilo with Thermage FLX, Ultherapy, or Picolaser in longer-term plans.

  • English level: English-speaking concierge; physicians use English with translation support as needed
  • Price range: ¥60,500–¥93,500 ($403–$623) per Profhilo session; Rejuran from ¥44,000 ($293)
  • Best for: patients wanting a side-by-side comparison of Profhilo vs other skin boosters
  • Caveat: aftercare products are strongly recommended and meaningfully increase the total spend

AOI 7 Clinic — Ginza

A newer aesthetic clinic in Ginza with dermatology and plastic surgery under one roof. Offers Profhilo, Rejuran, and HA-based skin boosters, and is useful if you want a Profhilo course coordinated with Thermage FLX, Silhouette Soft threads, or JSAPS-led surgical consultation in the same clinic.

  • English level: English-speaking receptionist; consultation via English-speaking doctor on select days
  • Price range: ¥55,000–¥88,000 ($367–$587) per Profhilo session
  • Best for: combination plans, patients coordinating multiple treatments under one roof
  • Caveat: the menu is wide — verify that the vial used is genuine Profhilo from IBSA rather than a generic skin booster mis-labeled in the consultation

Shinanozaka Clinic — Yotsuya / Shinjuku

A smaller, doctor-led practice that carries imported Profhilo on request, alongside Rejuran and Restylane Vital. Physicians include JSAPS/JSPRS-certified surgeons, and the clinic tends to be conservative about recommending Profhilo only when the indication matches the product.

  • English level: English consultations available with specific doctors by request
  • Price range: ¥71,500–¥104,500 ($477–$697) per session
  • Best for: patients wanting a conservative recommendation and a smaller clinic feel
  • Caveat: may suggest Rejuran or a device treatment instead if they think it's a better fit — some patients find that conversation frustrating when they came in with Profhilo in mind

Profhilo Tokyo Price Comparison (Tokyo, 2026)

Typical 2026 price ranges for Profhilo Tokyo patients are quoted, plus common skin booster alternatives for reference.

Product / Area Typical Range (¥) USD Equivalent Session Notes
Profhilo full face (2 ml, per session) ¥55,000–¥110,000 $367–$733 2 sessions, 4 weeks apart
Profhilo face course (2 sessions) ¥100,000–¥198,000 $667–$1,320 maintenance every 6 months
Profhilo neck / décolleté (per session) ¥66,000–¥121,000 $440–$807 2 sessions
Profhilo Body (arms / knees, per session) ¥88,000–¥165,000 $587–$1,100 2 sessions
Rejuran (per vial) ¥40,000–¥77,000 $267–$513 3–4 sessions, 2–4 weeks apart
Restylane Vital / Skinbooster (per ml) ¥45,000–¥88,000 $300–$587 3 sessions initial course
Juvederm Volite (per ml) ¥66,000–¥110,000 $440–$733 1 session, repeat at 9 months
Consultation fee ¥3,300–¥5,500 $22–$37 per visit

Prices are ranges across the clinics above at April 2026; confirm directly when booking. USD converted at ¥150 = $1.

Booking Profhilo in Tokyo Through Kanbi

Choosing a Profhilo Tokyo clinic as a foreigner means confirming the vial is genuine, privately-imported Profhilo with intact IBSA traceability, getting an honest read on whether bio-remodelling is actually the right fit versus a filler or Rejuran, and knowing realistic session and pricing expectations upfront. Kanbi matches you to an English-speaking clinic in Tokyo that carries genuine Profhilo, confirms the protocol and pricing before you book, and handles the Japanese-language communication. Submit a treatment request → kanbicare.com

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